{"id":1376545,"date":"2023-05-04T15:00:34","date_gmt":"2023-05-04T13:00:34","guid":{"rendered":"https:\/\/dnaera.com\/rs\/?p=1376545"},"modified":"2023-07-25T14:58:17","modified_gmt":"2023-07-25T12:58:17","slug":"puto-matka-a-dieta","status":"publish","type":"post","link":"https:\/\/dnaera.com\/rs\/blog\/puto-matka-a-dieta\/","title":{"rendered":"Skryt\u00e9 puto, ktor\u00e9 sp\u00e1ja matku a die\u0165a ne\u010dakan\u00fdm sp\u00f4sobom"},"content":{"rendered":"\n

O tom, \u017ee \u017eeny pred\u00e1vaj\u00fa svojmu die\u0165a\u0165u pribli\u017ene 50 % jeho DNA, ste u\u017e ur\u010dite po\u010duli. Menej zn\u00e1me, no nie a\u017e tak prekvapiv\u00e9 je, \u017ee bunky z tela matky sa v malej miere dost\u00e1vaj\u00fa do tela die\u0165a\u0165a, po\u010das toho ako sa vyv\u00edja. O \u010dom ste v\u0161ak e\u0161te asi nepo\u010duli je, \u017ee fet\u00e1lne bunky (bunky plodu) die\u0165a\u0165a si v sebe matky nes\u00fa a\u017e takmer 30 rokov po p\u00f4rode. <\/em><\/p>\n\n\n\n

Ako je to mo\u017en\u00e9?<\/h2>\n\n\n\n

Tento jav sa naz\u00fdva mikrochimerizmus a m\u00f4\u017ee by\u0165 odpove\u010fou na ot\u00e1zku, pre\u010do a\u017e 80 % \u013eud\u00ed, ktor\u00ed trpia autoimunitn\u00fdm ochoren\u00edm, s\u00fa \u017eeny, ale aj naopak, pre\u010do maj\u00fa \u017eeny, ktor\u00e9 rodili, ni\u017e\u0161iu \u0161ancu rozvoja rakoviny prsn\u00edka \u010di vaje\u010dn\u00edkov. Mikrochimerizmus je predmetom intenz\u00edvneho vedeck\u00e9ho sk\u00famania a m\u00f4\u017ee v\u00fdrazne zlep\u0161i\u0165 pochopenie zdravia \u017eien.<\/p>\n\n\n\n

Bunky jedn\u00e9ho organizmu sa stan\u00fa s\u00fa\u010das\u0165ou druh\u00e9ho<\/h2>\n\n\n\n

Mikrochimerizmus zjednodu\u0161ene predstavuje proces, pri ktorom sa bunky jedn\u00e9ho organizmu st\u00e1vaj\u00fa s\u00fa\u010das\u0165ou druh\u00e9ho organizmu. M\u00f4\u017ee sa vyskytova\u0165 po transplant\u00e1cii kostnej drene, krvn\u00fdch transf\u00fazi\u00e1ch alebo u dvoj\u010diat. No naj\u010dastej\u0161ou prirodzenou formou je pr\u00e1ve fet\u00e1lny mikrochimerizmus. <\/p>\n\n\n\n

Bunky vyv\u00edjaj\u00faceho sa plodu sa u\u017e v skor\u00fdch \u0161t\u00e1di\u00e1ch tehotenstva dost\u00e1vaj\u00fa cez placentu do krvn\u00e9ho obehu matky. To n\u00e1m umo\u017e\u0148uje robi\u0165 neinvaz\u00edvne prenat\u00e1lne testy z krvi matky, pri ktor\u00fdch je mo\u017en\u00e9 zisti\u0165 r\u00f4zne zmeny v DNA plodu. Tak\u00e9to fet\u00e1lne bunky v\u0161ak nezost\u00e1vaj\u00fa iba v krvi matky, ale niektor\u00e9 sa ukladaj\u00fa do r\u00f4znych org\u00e1nov a tkan\u00edv matky, kde zost\u00e1vaj\u00fa ulo\u017een\u00e9 aj nieko\u013eko desiatok rokov po p\u00f4rode. Jedn\u00fdm z t\u00fdchto org\u00e1nov je aj srdce matky.<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Ak\u00fd to m\u00e1 v\u0161ak v\u00fdznam? <\/h2>\n\n\n\n

Presn\u00fa odpove\u010f na t\u00fato ot\u00e1zku zatia\u013e nepozn\u00e1me. Jednou zo sk\u00faman\u00fdch mo\u017enost\u00ed je, \u017ee fet\u00e1lne bunky menia procesy v tele matky s cie\u013eom presun\u00fa\u0165 \u017eiviny smerom k plodu. V\u00fdskumy tie\u017e ukazuj\u00fa, \u017ee fet\u00e1lne bunky m\u00f4\u017eu napom\u00e1ha\u0165 \u017eensk\u00e9mu telu s hojen\u00edm.<\/strong> Po\u0161koden\u00e9 tkanivo matky (napr\u00edklad pri p\u00f4rode \u010di cis\u00e1rskom reze) vysiela sign\u00e1ly, ktor\u00e9 na toto miesto pril\u00e1kaj\u00fa mikrochimerick\u00e9 fet\u00e1lne bunky. Tie vedia produkova\u0165 kolag\u00e9n a in\u00e9 faktory, ktor\u00e9 ur\u00fdch\u013euj\u00fa hojenie. Podobne protekt\u00edvny vplyv t\u00fdchto buniek nazna\u010duj\u00fa aj \u0161t\u00fadie, ktor\u00e9 sledovali ni\u017e\u0161\u00ed v\u00fdskyt rakoviny prsn\u00edka \u010di vaje\u010dn\u00edkov u \u017eien, ktor\u00e9 mali deti. Vy\u0161\u0161ie mno\u017estvo tak\u00fdchto buniek bolo pozorovan\u00e9 aj v n\u00e1dorovom tkanive u \u017eien, ktor\u00e9 mali rakovinu p\u013e\u00fac aj desiatky rokov po p\u00f4rode, \u010do by mohlo vysvetli\u0165 ich lep\u0161iu progn\u00f3zu v porovnan\u00ed so \u017eenami, ktor\u00e9 deti nemali. <\/p>\n\n\n\n

Na druhej strane, pr\u00e1ve pr\u00edtomnos\u0165 buniek plodu v tele matky aj dlho po p\u00f4rode m\u00f4\u017ee by\u0165 spojen\u00e1 s \u010dastej\u0161\u00edm vznikom autoimunitn\u00fdch ochoren\u00ed u \u017eien. <\/strong>Napr\u00edklad skleroderma sa prim\u00e1rne vyskytuje u \u017eien v pop\u00f4rodnom veku. Pr\u00edznaky tohto ochorenia v\u00fdznamne pripom\u00ednaj\u00fa ne\u017eiaducu reakciu hostite\u013ea na darovan\u00fd org\u00e1n (GVHD). U \u017eien s t\u00fdmto ochoren\u00edm boli n\u00e1jden\u00e9 fet\u00e1lne bunky s Y chromoz\u00f3mom aj desiatky rokov po p\u00f4rode. Ke\u010f\u017ee sa Y chromoz\u00f3m v \u017eensk\u00fdch bunk\u00e1ch nenach\u00e1dza, tieto bunky poch\u00e1dzaj\u00fa pr\u00e1ve z plodu mu\u017esk\u00e9ho pohlavia. <\/p>\n\n\n\n

Puto medzi die\u0165a\u0165om a matkou je ve\u013emi siln\u00e9 <\/h2>\n\n\n\n

Aj ke\u010f m\u00e1 v\u00fdskum mikrochimerizmu pred sebou e\u0161te dlh\u00fa cestu, u\u017e teraz je jasn\u00e9, \u017ee materstvo men\u00ed \u017eivot \u017eien aj na tej najmen\u0161ej – bunkovej \u00farovni<\/strong>. Ak chcete svoju maminu pote\u0161i\u0165 a prekvapi\u0165 po\u010das D\u0148a matiek, darujte jej napr\u00edklad DNA Health test<\/a>, v\u010faka ktor\u00e9mu bude m\u00f4c\u0165 zlep\u0161i\u0165 svoj \u017eivotn\u00fd \u0161t\u00fdl a celkov\u00e9 zdravie. <\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Zdroje:<\/strong><\/p>\n\n\n\n

    \n
  1. Shrivastava, S., Naik, R., Suryawanshi, H., & Gupta, N. (2019). Microchimerism: A new concept. Journal of oral and maxillofacial pathology: JOMFP<\/em>, 23<\/em>(2), 311.<\/li>\n\n\n\n
  2. O’Donoghue, K. (2008). Fetal microchimerism and maternal health during and after pregnancy. Obstetric medicine, 1(2), 56-64.<\/li>\n\n\n\n
  3. https:\/\/www.smithsonianmag.com\/science-nature\/babys-cells-can-manipulate-moms-body-decades-180956493\/<\/li>\n<\/ol>\n\n\n\n

    <\/p>\n\n\n\n

    Zdoje fotografi\u00ed:<\/strong><\/p>\n\n\n\n

      \n
    1. https:\/\/www.freepik.com\/free-photo\/young-mother-with-her-one-years-old-little-son-dressed-pajamas-are-relaxing_10271349.htm#page=3&query=mother%20and%20child&position=46&from_view=search&track=ais<\/a><\/li>\n\n\n\n
    2. https:\/\/www.pexels.com\/photo\/happy-affectionate-family-4609033\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

      O tom, \u017ee \u017eeny pred\u00e1vaj\u00fa svojmu die\u0165a\u0165u pribli\u017ene 50 % jeho DNA, ste u\u017e ur\u010dite po\u010duli. Menej zn\u00e1me, no nie a\u017e tak prekvapiv\u00e9 je, \u017ee bunky z tela matky sa v malej miere dost\u00e1vaj\u00fa do tela die\u0165a\u0165a, po\u010das toho ako sa vyv\u00edja. O \u010dom ste v\u0161ak e\u0161te asi nepo\u010duli je, \u017ee fet\u00e1lne bunky (bunky plodu) […]<\/p>\n","protected":false},"author":6,"featured_media":1376547,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[60,63],"place-taxonomy":[],"class_list":["post-1376545","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-sk","tag-genetika","tag-zaujimavosti"],"acf":[],"views":3072,"_links":{"self":[{"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/posts\/1376545","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/comments?post=1376545"}],"version-history":[{"count":5,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/posts\/1376545\/revisions"}],"predecessor-version":[{"id":1378152,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/posts\/1376545\/revisions\/1378152"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/media\/1376547"}],"wp:attachment":[{"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/media?parent=1376545"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/categories?post=1376545"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/tags?post=1376545"},{"taxonomy":"place-taxonomy","embeddable":true,"href":"https:\/\/dnaera.com\/rs\/wp-json\/wp\/v2\/place-taxonomy?post=1376545"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}