{"id":1377572,"date":"2023-07-25T14:55:55","date_gmt":"2023-07-25T12:55:55","guid":{"rendered":"https:\/\/dnaera.com\/ro\/?p=1377572"},"modified":"2023-08-14T08:59:31","modified_gmt":"2023-08-14T06:59:31","slug":"nemelanomova-rakovina-koze","status":"publish","type":"post","link":"https:\/\/dnaera.com\/ro\/blog\/nemelanomova-rakovina-koze\/","title":{"rendered":"Nemelan\u00f3mov\u00e1 rakovina ko\u017ee – probl\u00e9mom nemusia by\u0165 iba znamienka"},"content":{"rendered":"\n

Ko\u017ea predstavuje \u00fa\u010dinn\u00fa bari\u00e9ru, ktor\u00e1 n\u00e1s chr\u00e1ni pred vplyvmi vonkaj\u0161ieho prostredia, patog\u00e9nmi, chladom \u010di teplom. V\u010faka ve\u013ek\u00e9mu mno\u017estvu citliv\u00fdch buniek v ko\u017ei c\u00edtime dotyk, boles\u0165 alebo tlak. \u010cinnos\u0165ou slne\u010dn\u00e9ho \u017eiarenia sa v ko\u017ei tvor\u00ed vitam\u00edn D, ktor\u00fd m\u00e1 v tele viacer\u00e9 nezastupite\u013en\u00e9 funkcie. Dopad UV \u017eiarenia na na\u0161u ko\u017eu je teda potrebn\u00fd, av\u0161ak pri nadmernom p\u00f4soben\u00ed m\u00f4\u017ee vies\u0165 k vzniku rakoviny ko\u017ee. P\u00f4sobenie UV \u017eiarenia toti\u017e vedie k vzniku po\u0161koden\u00ed v DNA, teda mut\u00e1ci\u00e1m. Pr\u00e1ve tieto zmeny ved\u00fa k vzniku n\u00e1dorov\u00fdch buniek, ktor\u00e9 sa z ko\u017ee m\u00f4\u017eu \u0161\u00edri\u0165 aj do \u010fal\u0161\u00edch \u010dast\u00ed tela. K skorej diagnostike m\u00f4\u017ee pom\u00f4c\u0165 aj poznanie genetickej predispoz\u00edcie. Na\u0161i existuj\u00faci z\u00e1kazn\u00edci si vo svojich v\u00fdsledkoch n\u00e1jdu zdarma nov\u00fd v\u00fdsledok zaraden\u00fd v kateg\u00f3rii Zdravie. <\/em><\/p>\n\n\n\n

Existuje melan\u00f3mov\u00e1 a nemelan\u00f3mov\u00e1 rakovina ko\u017ee<\/h2>\n\n\n\n

Najz\u00e1kernej\u0161iu formu rakoviny ko\u017ee predstavuje melan\u00f3m, ktor\u00fd postihuje bunky produkuj\u00face ko\u017en\u00e9 farbivo – melanocyty. Ten v\u0161ak tvor\u00ed pribli\u017ene iba 1 % pr\u00edpadov rakoviny ko\u017ee. Viac o melan\u00f3me si m\u00f4\u017eete pre\u010d\u00edta\u0165 v na\u0161om<\/a> blogu. A\u017e 99 % pr\u00edpadov rakoviny ko\u017ee tvoria ochorenia so spolo\u010dn\u00fdm n\u00e1zvom nemelan\u00f3mov\u00e1 rakovina ko\u017ee. <\/p>\n\n\n\n

Rakovina ko\u017ee sa nemus\u00ed vyskytova\u0165 iba v znamienkach<\/h2>\n\n\n\n

Ke\u010f\u017ee znamienka obsahuj\u00fa ve\u013ek\u00e9 mno\u017estvo melanocytov, predstavuj\u00fa rizikov\u00e9 miesta pre vznik rakoviny ko\u017ee. Nemelan\u00f3mov\u00e1 rakovina ko\u017ee sa v\u0161ak vyskytuje v\u00e4\u010d\u0161inou pr\u00e1ve mimo nich a postihuje hlavne bunky poko\u017eky (keratinocyty) a baz\u00e1lne bunky, z ktor\u00fdch sa keratinocyty tvoria. Bazocelul\u00e1rny karcin\u00f3m vyzer\u00e1 typicky ako perle\u0165ov\u00fd alebo voskov\u00fd hrbol\u010dek na ko\u017ei s \u010dasto vidite\u013en\u00fdmi krvn\u00fdmi cievami. Spinocelul\u00e1rny karcin\u00f3m v\u00e4\u010d\u0161inou vyzer\u00e1 ako \u0161upinat\u00fd, ru\u017eov\u00fd \u010di \u010derven\u00fd hrbol\u010dek, pr\u00edpadne ako stvrdnut\u00e1 \u0161kvrna na ko\u017ei. <\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Hlavn\u00fdm rizikov\u00fdm faktorom pre vznik rakoviny ko\u017ee je UVB \u017eiarenie<\/h2>\n\n\n\n

UVB \u017eiarenie je typ slne\u010dn\u00e9ho UV \u017eiarenia, ktor\u00e9 je zodpovedn\u00e9 za sp\u00e1lenie ko\u017ee, a s n\u00edm spojen\u00fdmi zmenami v DNA. \u00da\u010dinnou ochranou je vyh\u00fdbanie sa slne\u010dn\u00fdm l\u00fa\u010dom (najm\u00e4 medzi 10:00 a 16:00 hodinou), nosenie ochrann\u00e9ho oble\u010denia, pokr\u00fdvky hlavy a v prvom rade spr\u00e1vna aplik\u00e1cia opa\u013eovacieho kr\u00e9mu s ochrann\u00fdm faktorom aspo\u0148 30. Do rizikovej skupiny patria najm\u00e4 \u013eudia so svetl\u00fdm typom pleti, \u010dast\u00ed n\u00e1v\u0161tevn\u00edci sol\u00e1ri\u00ed, faj\u010diari, \u010di \u013eudia s oslabenou imunitou. Obzvl\u00e1\u0161\u0165 d\u00f4le\u017eit\u00e9 je chr\u00e1ni\u0165 pred sp\u00e1len\u00edm mal\u00e9 deti, ke\u010f\u017ee ka\u017ed\u00e9 sp\u00e1lenie po\u010das \u017eivota zvy\u0161uje riziko. <\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Vplyv maj\u00fa aj na\u0161e g\u00e9ny<\/h2>\n\n\n\n

U niektor\u00fdch \u013eud\u00ed vznikaj\u00fa zmeny na ko\u017ei, ktor\u00e9 mo\u017eu vies\u0165 k vzniku nemelan\u00f3movej rakoviny ko\u017ee o nie\u010do \u013eah\u0161ie ako u in\u00fdch. Tieto g\u00e9ny sa podie\u013eaj\u00fa na tvorbe melan\u00ednu, ktor\u00fd chr\u00e1ni poko\u017eku pred UV \u017eiaren\u00edm, zabra\u0148uj\u00fa nekontrolovate\u013en\u00e9mu deleniu buniek alebo pom\u00e1haj\u00fa udr\u017eiava\u0165 stabilitu chromoz\u00f3mov v jadre bunky. Pr\u00edtomnos\u0165 ur\u010dit\u00fdch genetick\u00fdch variantov v DNA v\u00e1s teda m\u00f4\u017ee robi\u0165 n\u00e1chylnej\u0161\u00edch na rozvoj nemelan\u00f3movej rakoviny ko\u017ee. <\/p>\n\n\n\n

Nov\u00fd v\u00fdsledok anal\u00fdzy<\/h2>\n\n\n\n

O svojom genetickom riziku na rozvoj tohto ochorenia a \u010fal\u0161\u00edch inform\u00e1ci\u00e1ch t\u00fdkaj\u00facich sa nemelan\u00f3movej rakoviny ko\u017ee sa dozviete vo svojich v\u00fdsledkoch. Prihl\u00e1ste sa do svojho \u00fa\u010dtu<\/a><\/strong> a dodr\u017eiavajte z\u00e1kladn\u00e9 prevent\u00edvne opatrenia. Nov\u00fd v\u00fdsledok z\u00edskaj\u00fa aj v\u0161etci bud\u00faci z\u00e1kazn\u00edci, ktor\u00ed si objednaj\u00fa DNA Complex test<\/a> alebo DNA Health test<\/a>. V r\u00e1mci roz\u0161\u00edren\u00ed ho m\u00f4\u017eu priamo vo svojich v\u00fdsledkoch bez potreby opakovanie odberu vzorky z\u00edska\u0165 aj v\u0161etci ostatn\u00ed z\u00e1kazn\u00edci. <\/p>\n\n\n\n

Zdroje:<\/strong><\/p>\n\n\n\n

    \n
  1. Gordon, R. (2013, August). Skin cancer: an overview of epidemiology and risk factors. In Seminars in oncology nursing (Vol. 29, No. 3, pp. 160-169). WB Saunders.<\/li>\n\n\n\n
  2. https:\/\/www.nhs.uk\/conditions\/non-melanoma-skin-cancer\/<\/a><\/li>\n\n\n\n
  3. https:\/\/www.cancer.net\/cancer-types\/skin-cancer-non-melanoma\/risk-factors-and-prevention<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Ko\u017ea predstavuje \u00fa\u010dinn\u00fa bari\u00e9ru, ktor\u00e1 n\u00e1s chr\u00e1ni pred vplyvmi vonkaj\u0161ieho prostredia, patog\u00e9nmi, chladom \u010di teplom. V\u010faka ve\u013ek\u00e9mu mno\u017estvu citliv\u00fdch buniek v ko\u017ei c\u00edtime dotyk, boles\u0165 alebo tlak. \u010cinnos\u0165ou slne\u010dn\u00e9ho \u017eiarenia sa v ko\u017ei tvor\u00ed vitam\u00edn D, ktor\u00fd m\u00e1 v tele viacer\u00e9 nezastupite\u013en\u00e9 funkcie. Dopad UV \u017eiarenia na na\u0161u ko\u017eu je teda potrebn\u00fd, av\u0161ak pri nadmernom […]<\/p>\n","protected":false},"author":6,"featured_media":1377575,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[58,59],"place-taxonomy":[],"class_list":["post-1377572","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-sk","tag-dna-analyza","tag-dna-test"],"acf":[],"views":3935,"_links":{"self":[{"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/posts\/1377572","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/comments?post=1377572"}],"version-history":[{"count":5,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/posts\/1377572\/revisions"}],"predecessor-version":[{"id":1378210,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/posts\/1377572\/revisions\/1378210"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/media\/1377575"}],"wp:attachment":[{"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/media?parent=1377572"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/categories?post=1377572"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/tags?post=1377572"},{"taxonomy":"place-taxonomy","embeddable":true,"href":"https:\/\/dnaera.com\/ro\/wp-json\/wp\/v2\/place-taxonomy?post=1377572"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}