{"id":1390465,"date":"2024-03-21T14:06:07","date_gmt":"2024-03-21T13:06:07","guid":{"rendered":"https:\/\/dnaera.com\/hu\/?p=1390465"},"modified":"2024-05-28T09:54:26","modified_gmt":"2024-05-28T07:54:26","slug":"vitaminy-a-mineraly","status":"publish","type":"post","link":"https:\/\/dnaera.com\/hu\/blog\/vitaminy-a-mineraly\/","title":{"rendered":"Nie v\u0161etky stravovacie odpor\u00fa\u010dania s\u00fa 100% vhodn\u00e9 pre ka\u017ed\u00e9ho: Ak\u00e9 vitam\u00edny a miner\u00e1ly ovplyv\u0148uj\u00fa na\u0161e g\u00e9ny?"},"content":{"rendered":"\n

Vyv\u00e1\u017een\u00e1 strava a fyzick\u00e1 aktivita zohr\u00e1vaj\u00fa nepopierate\u013en\u00fa \u00falohu v starostlivosti o zdravie. Av\u0161ak nie ka\u017ed\u00e9 odpor\u00fa\u010danie mus\u00ed 100% vyhovova\u0165 ka\u017ed\u00e9mu. V\u00fd\u017eivov\u00e9 a fyzick\u00e9 potreby jednotliv\u00fdch \u013eud\u00ed sa m\u00f4\u017eu l\u00ed\u0161i\u0165 v z\u00e1vislosti od veku, pohlavia a zdravotn\u00e9ho stavu, ale aj od konkr\u00e9tnych g\u00e9nov, ktor\u00e9 m\u00e1me v DNA. Anal\u00fdza genetick\u00fdch predispoz\u00edci\u00ed v\u00e1m m\u00f4\u017ee pom\u00f4c\u0165 zodpoveda\u0165 d\u00f4le\u017eit\u00e9 ot\u00e1zky s\u00favisiace s hladinou miner\u00e1lov a vitam\u00ednov vo va\u0161om tele. V\u00fdsledok DNA anal\u00fdzy v\u00e1m nazna\u010d\u00ed, ktor\u00e9 nutri\u010dn\u00e9 \u200b\u200ba zdravotn\u00e9 parametre sa m\u00f4\u017eu odchy\u013eova\u0165 od normy a ktor\u00e9 z nich sa odpor\u00fa\u010da potvrdi\u0165 testami alebo podrobi\u0165 zv\u00fd\u0161enej prevencii.<\/em><\/em><\/p>\n\n\n\n

Ako na\u0161e g\u00e9ny ovplyv\u0148uj\u00fa \u017eiviny v tele? Pre\u010d\u00edtajte si konkr\u00e9tne pr\u00edklady<\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Vitam\u00edn D<\/strong><\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Asi jedna miliarda \u013eud\u00ed na celom svete trp\u00ed nedostatkom vitam\u00ednu D. Tento probl\u00e9m sa t\u00fdka a\u017e 40 % Eur\u00f3panov. Jednou z najd\u00f4le\u017eitej\u0161\u00edch funkci\u00ed tohto vitam\u00ednu je podpora vstreb\u00e1vania v\u00e1pnika z tenk\u00e9ho \u010dreva do krvn\u00e9ho obehu. Vitam\u00edn D je tie\u017e d\u00f4le\u017eit\u00fd pre zabezpe\u010denie st\u00e1lej rovnov\u00e1hy v\u00e1pnika a fosforu v krvi, \u010d\u00edm je jeho \u00faloha pri mineraliz\u00e1cii kost\u00ed a zubov nezastupite\u013en\u00e1. Prispieva tie\u017e k spr\u00e1vnemu fungovaniu imunitn\u00e9ho syst\u00e9mu a m\u00f4\u017ee zn\u00ed\u017ei\u0165 riziko depresie. Dospel\u00ed by mali denne prija\u0165 aspo\u0148 1000-2000 IU vitam\u00ednu D.<\/p>\n\n\n\n

Poznanie va\u0161ej genetickej predispoz\u00edcie na zn\u00ed\u017een\u00fa hladiny vitam\u00ednu D v krvi v\u00e1s m\u00f4\u017ee povzbudi\u0165 k tomu, aby ste po\u010das lek\u00e1rskych prehliadok pozorne sledovali jeho hladinu. Z\u00e1rove\u0148 m\u00f4\u017ee by\u0165 \u0165a\u017ek\u00e9 udr\u017ea\u0165 ho na primeranej \u00farovni prostredn\u00edctvom stravy a vystavenia slne\u010dn\u00e9mu \u017eiareniu. V pr\u00edpade vitam\u00ednu D m\u00f4\u017ee by\u0165 suplement\u00e1cia najvhodnej\u0161\u00edm sp\u00f4sobom, ako zabezpe\u010di\u0165 jeho primeran\u00e9 mno\u017estvo, najm\u00e4 v zimn\u00fdch mesiacoch, ke\u010f nesvieti slnko.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Omega-3 mastn\u00e9 kyseliny<\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Mnoho \u013eud\u00ed m\u00e1 predispoz\u00edciu k zv\u00fd\u0161enej potrebe omega-3 mastn\u00fdch kysel\u00edn, ktor\u00e9 hraj\u00fa k\u013e\u00fa\u010dov\u00fa \u00falohu vo fungovan\u00ed mozgu, imunitn\u00e9ho syst\u00e9mu a obehov\u00e9ho syst\u00e9mu.<\/p>\n\n\n\n

Imunitn\u00fd syst\u00e9m \u010dloveka chr\u00e1ni na\u0161e telo nielen pred vonkaj\u0161\u00edmi patog\u00e9nmi, ako s\u00fa bakt\u00e9rie a v\u00edrusy, ale aj pred vn\u00fatorn\u00fdm po\u0161koden\u00edm a dysfunkciou tkan\u00edv. Jednou z prv\u00fdch ochrann\u00fdch bari\u00e9r je z\u00e1pal, ktor\u00fd je s\u00fa\u010das\u0165ou vrodenej imunity. K\u013e\u00fa\u010dov\u00fa \u00falohu pri regul\u00e1cii z\u00e1palovej odpovede hr\u00e1 cytok\u00edn TNF (tumor nekrotizuj\u00faci faktor). Je zn\u00e1me, \u017ee polymorfizmy v g\u00e9ne k\u00f3duj\u00facom tento cytok\u00edn maj\u00fa vplyv na jeho hladinu. Zv\u00fd\u0161en\u00e1 koncentr\u00e1cia cytok\u00ednu m\u00f4\u017ee vies\u0165 k nadmernej z\u00e1palovej reakcii, \u00fanave, zv\u00fd\u0161en\u00e9mu riziku vzniku cukrovky a kardiovaskul\u00e1rnych ochoren\u00ed \u010di pomal\u0161ej regener\u00e1cii po cvi\u010den\u00ed. Omega-3 mastn\u00e9 kyseliny pom\u00e1haj\u00fa tak\u00fdto z\u00e1pal v tele zni\u017eova\u0165.<\/p>\n\n\n\n

Odpor\u00fa\u010dan\u00fd denn\u00fd pr\u00edjem omega-3 mastn\u00fdch kysel\u00edn je 1,6 g pre mu\u017eov a 1,1 g pre \u017eeny. Ak m\u00e1te predispoz\u00edciu na zv\u00fd\u0161en\u00e9 hladiny proz\u00e1palov\u00e9ho cytok\u00ednu TNF, odpor\u00fa\u010da sa zv\u00fd\u0161i\u0165 d\u00e1vku na 3 g denne a na 2 g, ak m\u00e1te predispoz\u00edciu na mierne zv\u00fd\u0161en\u00e9 hladiny.<\/p>\n\n\n\n

\u017delezo<\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

\u017delezo je jedn\u00fdm zo z\u00e1kladn\u00fdch miner\u00e1lov pre fungovanie n\u00e1\u0161ho tela. Je s\u00fa\u010das\u0165ou mnoh\u00fdch prote\u00ednov vr\u00e1tane hemoglob\u00ednu, ktor\u00fd je zodpovedn\u00fd za transport kysl\u00edka z p\u013e\u00fac do v\u0161etk\u00fdch buniek tela, a myoglob\u00ednu, ktor\u00fd umo\u017e\u0148uje svalom prij\u00edma\u0165 kysl\u00edk z krvi. An\u00e9mia alebo nedostatok \u017eeleza je jedn\u00fdm z najbe\u017enej\u0161\u00edch v\u00fd\u017eivov\u00fdch nedostatkov na svete.<\/p>\n\n\n\n

Hoci je \u017eelezo nevyhnutnou s\u00fa\u010das\u0165ou stravy, pr\u00edli\u0161 ve\u013ek\u00e9 mno\u017estvo m\u00f4\u017ee \u0161kodi\u0165 v\u00e1\u0161mu zdraviu. Niektor\u00e9 genetick\u00e9 polymorfizmy sp\u00f4sobuj\u00fa zv\u00fd\u0161en\u00fa absorpciu \u017eeleza, \u010do vedie k nadbytku \u017eeleza napriek konzum\u00e1cii be\u017en\u00fdch mno\u017estiev v strave.<\/p>\n\n\n\n

Hemochromat\u00f3za, ochorenie charakterizovan\u00e9 nadmern\u00fdm vstreb\u00e1van\u00edm \u017eeleza v tenkom \u010dreve, je jedn\u00fdm z naj\u010dastej\u0161\u00edch genetick\u00fdch ochoren\u00ed. Toto ochorenie sa vyv\u00edja postupne, a preto sa zvy\u010dajne prejavuje po 40. roku \u017eivota. M\u00f4\u017ee vies\u0165 k po\u0161kodeniu org\u00e1nov, cirh\u00f3ze pe\u010dene, hepatocelul\u00e1rnemu karcin\u00f3mu a cukrovke.<\/p>\n\n\n\n

V\u010dasn\u00e1 diagnostika m\u00e1 v\u00fdznamn\u00fd vplyv na progresiu hemochromat\u00f3zy. Kv\u00f4li ne\u0161pecifick\u00fdm pr\u00edznakom je toto ochorenie \u010dasto diagnostikovan\u00e9 pr\u00edli\u0161 neskoro. Anal\u00fdza DNA v\u00e1m m\u00f4\u017ee pom\u00f4c\u0165 odhali\u0165 tento potenci\u00e1lny zdravotn\u00fd probl\u00e9m alebo poskytn\u00fa\u0165 odpovede na to, \u010di m\u00f4\u017ee by\u0165 v\u00e1\u0161 potomok ohrozen\u00fd. V\u010dasn\u00e1 lie\u010dba je ve\u013emi \u00fa\u010dinn\u00e1 a m\u00f4\u017ee \u00faplne zastavi\u0165 po\u0161kodenie org\u00e1nov, \u010do v\u00e1m umo\u017en\u00ed vies\u0165 norm\u00e1lny \u017eivot.<\/p>\n\n\n\n

Takmer 30 % na\u0161ej popul\u00e1cie je pren\u00e1\u0161a\u010dom tejto choroby, \u010di\u017ee \u0148ou nie s\u00fa postihnut\u00ed, ale m\u00f4\u017eu ju prenies\u0165 na svoje deti.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Magn\u00e9zium<\/strong><\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Hor\u010d\u00edk je mikroelement, ktor\u00fd sa nach\u00e1dza v\u0161ade, \u010di u\u017e na zemi, v oce\u00e1noch, rastlin\u00e1ch, ale aj v \u013eudskom tele. Asi 60 % hor\u010d\u00edka v na\u0161om tele sa nach\u00e1dza v kostiach a zvy\u0161ok vo svaloch, m\u00e4kk\u00fdch tkaniv\u00e1ch a tekutin\u00e1ch vr\u00e1tane krvi. Koncentr\u00e1cia hor\u010d\u00edka v krvi je spojen\u00e1 s polymorfizmami v mnoh\u00fdch g\u00e9noch.<\/p>\n\n\n\n

Hor\u010d\u00edk hr\u00e1 \u00falohu v biochemick\u00fdch reakci\u00e1ch, kde p\u00f4sob\u00ed ako kofaktor alebo \u201epomocn\u00e1 molekula\u201c. Podie\u013ea sa na viac ako 600 reakci\u00e1ch v tele. Prakticky ka\u017ed\u00e1 bunka v na\u0161om tele potrebuje na svoje fungovanie hor\u010d\u00edk. Hladinu hor\u010d\u00edka v krvi reguluj\u00fa najm\u00e4 obli\u010dky. Pod\u013ea vedeck\u00fdch zdrojov pribli\u017ene 50 % \u013eud\u00ed v USA a Eur\u00f3pe prij\u00edma menej ako je odpor\u00fa\u010dan\u00e9 mno\u017estvo hor\u010d\u00edka denne. Jeho nedostatok m\u00f4\u017ee vies\u0165 k mnoh\u00fdm zdravotn\u00fdm probl\u00e9mom, ako s\u00fa poruchy srdcov\u00e9ho rytmu, svalov\u00e9 k\u0155\u010de (hlavne po intenz\u00edvnom tr\u00e9ningu), nespavos\u0165 \u010di zv\u00fd\u0161en\u00e1 podr\u00e1\u017edenos\u0165. Odpor\u00fa\u010dan\u00e1 denn\u00e1 d\u00e1vka hor\u010d\u00edka je 400\u2013420 mg pre mu\u017eov a 310\u2013320 mg pre \u017eeny.<\/p>\n\n\n\n

Zdroje<\/strong>: <\/p>\n\n\n\n

    \n
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  2. Revez, J. A., Lin, T., Qiao, Z., Xue, A., Holtz, Y., Zhu, Z., … & McGrath, J. J. (2020). Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. Nature communications, 11(1), 1-12.<\/li>\n\n\n\n
  3. Cheng, Y. C., Huang, Y. C., & Huang, W. L. (2020). The effect of vitamin D supplement on negative emotions: A systematic review and meta\u2010analysis. Depression and anxiety, 37(6), 549-564.<\/li>\n\n\n\n
  4. https:\/\/ods.od.nih.gov\/factsheets\/VitaminD-HealthProfessional\/<\/a><\/li>\n\n\n\n
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  7. Coates, T. D., & Cazzola, M. (2019). Introduction to a review series on iron metabolism and its disorders.<\/li>\n\n\n\n
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  10. Meyer, T. E., Verwoert, G. C., Hwang, S. J., Glazer, N. L., Smith, A. V., Van Rooij, F. J., … & Harris, T. B. (2010). Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. PLoS genetics, 6(8).<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Vyv\u00e1\u017een\u00e1 strava a fyzick\u00e1 aktivita zohr\u00e1vaj\u00fa nepopierate\u013en\u00fa \u00falohu v starostlivosti o zdravie. Av\u0161ak nie ka\u017ed\u00e9 odpor\u00fa\u010danie mus\u00ed 100% vyhovova\u0165 ka\u017ed\u00e9mu. V\u00fd\u017eivov\u00e9 a fyzick\u00e9 potreby jednotliv\u00fdch \u013eud\u00ed sa m\u00f4\u017eu l\u00ed\u0161i\u0165 v z\u00e1vislosti od veku, pohlavia a zdravotn\u00e9ho stavu, ale aj od konkr\u00e9tnych g\u00e9nov, ktor\u00e9 m\u00e1me v DNA. 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